Example dataset Model data using Principal Components analysis
perform_pca.RdPerform data modelling using principal components analysis
Author
Miss Oriade Latifah Simpson, s172084@dtu.dk
Examples
data("wide_wide_west")
west_data_wide
#> # A tibble: 49 × 101
#> value gene_132 gene_1475 gene_6915 gene_117 gene_3068 gene_2046 gene_452
#> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
#> 1 1 -0.867 -0.0516 -0.867 1.43 1.05 -0.00659 -0.819
#> 2 1 -0.830 0.133 -0.509 0.455 0.981 0.361 -0.830
#> 3 1 0.0121 -0.383 -0.849 1.50 0.924 -0.756 -0.425
#> 4 1 -0.820 -0.445 -0.804 0.0512 1.19 0.130 -0.820
#> 5 1 -0.828 0.0426 -0.639 1.21 0.841 0.0621 0.128
#> 6 1 -0.788 0.00666 -0.0769 1.28 0.691 -0.442 -0.788
#> 7 0 0.933 -0.888 1.17 2.46 0.435 0.931 0.0815
#> 8 0 0.157 -0.944 1.24 2.26 -0.944 0.875 -0.944
#> 9 0 0.529 -0.252 1.26 0.666 0.992 0.557 -0.184
#> 10 0 0.452 -0.328 0.133 2.01 0.993 0.222 -0.480
#> # … with 39 more rows, and 93 more variables: gene_6962 <dbl>, gene_2773 <dbl>,
#> # gene_5886 <dbl>, gene_121 <dbl>, gene_4016 <dbl>, gene_4373 <dbl>,
#> # gene_1194 <dbl>, gene_1933 <dbl>, gene_4843 <dbl>, gene_3400 <dbl>,
#> # gene_4643 <dbl>, gene_6708 <dbl>, gene_6086 <dbl>, gene_6341 <dbl>,
#> # gene_4213 <dbl>, gene_4582 <dbl>, gene_4585 <dbl>, gene_5718 <dbl>,
#> # gene_79 <dbl>, gene_6660 <dbl>, gene_4803 <dbl>, gene_1621 <dbl>,
#> # gene_2065 <dbl>, gene_5055 <dbl>, gene_119 <dbl>, gene_6256 <dbl>, …
pca_fit <- perform_pca(west_data_wide)
pca_fit
#> Standard deviations (1, .., p=49):
#> [1] 4.925091e+00 2.756506e+00 2.533162e+00 2.427195e+00 2.197569e+00
#> [6] 1.980577e+00 1.874679e+00 1.728755e+00 1.715541e+00 1.698700e+00
#> [11] 1.643978e+00 1.492817e+00 1.467877e+00 1.447875e+00 1.358341e+00
#> [16] 1.320198e+00 1.303636e+00 1.264349e+00 1.188261e+00 1.181801e+00
#> [21] 1.148606e+00 1.132141e+00 1.086157e+00 1.066809e+00 1.015568e+00
#> [26] 9.942341e-01 9.355425e-01 9.166335e-01 8.766331e-01 8.439082e-01
#> [31] 8.338879e-01 8.183301e-01 7.846885e-01 7.408069e-01 7.130903e-01
#> [36] 7.074581e-01 6.648286e-01 6.276274e-01 5.983778e-01 5.933293e-01
#> [41] 5.668652e-01 5.351202e-01 5.038244e-01 4.736358e-01 4.282910e-01
#> [46] 3.774434e-01 3.625219e-01 3.374298e-01 2.187180e-15
#>
#> Rotation (n x k) = (101 x 49):
#> PC1 PC2 PC3 PC4 PC5
#> value -0.16622538 -0.0167337708 -0.044769064 -0.0226381960 -0.0057834085
#> gene_132 0.14048774 0.0001316681 0.119102499 -0.0339014483 -0.0374129666
#> gene_1475 -0.14545092 -0.1158959138 -0.010161575 0.0623801659 -0.0062107243
#> gene_6915 0.11309689 -0.2022232703 0.045240167 0.0333985268 -0.0731736411
#> gene_117 0.10632081 -0.0390881489 0.230201963 -0.1524693094 0.0410237656
#> gene_3068 -0.13949848 0.1306389954 -0.024142091 0.1065329551 -0.0291911904
#> gene_2046 0.11062324 -0.1668707533 -0.046802027 0.0160607981 0.0080425312
#> gene_452 0.10418459 0.0537086564 0.065984660 0.0664639385 -0.0461553690
#> gene_6962 -0.13325500 -0.0887992366 0.011783372 0.0943942085 -0.0957384467
#> gene_2773 -0.10927582 -0.0891050491 0.087702700 -0.0841924238 0.1221944708
#> gene_5886 -0.10606946 0.0459504988 -0.043872087 -0.1915534264 0.0171737526
#> gene_121 0.09120080 0.0777421004 0.202749579 -0.2101858383 -0.0217658815
#> gene_4016 -0.09322670 -0.0788803063 0.069753136 -0.1056159265 0.0902251022
#> gene_4373 -0.09795646 0.1896238483 0.010805082 -0.0518657798 -0.0131533620
#> gene_1194 0.09860349 0.0720060179 -0.029141340 0.0848656387 -0.0159725367
#> gene_1933 0.10590633 0.0532597916 -0.010720936 0.0303145691 0.1190532858
#> gene_4843 -0.11510102 -0.1026486299 0.028889075 -0.0931194981 0.0992534360
#> gene_3400 0.08818628 0.0314619438 0.106778797 0.1271899024 -0.0030512520
#> gene_4643 0.11536560 -0.1725762474 0.038407932 -0.0232543722 0.0785013963
#> gene_6708 -0.12939052 -0.0224838774 -0.065997721 0.0376165395 0.0988600206
#> gene_6086 -0.08570302 -0.1780730133 0.025079155 0.0810167115 0.0444494302
#> gene_6341 -0.09545809 -0.0592641898 -0.026368985 -0.0711573720 0.1314195819
#> gene_4213 -0.12587528 0.1318553218 0.100670308 0.0849255368 0.0290015660
#> gene_4582 -0.13079678 -0.0674911860 -0.034496832 0.0707006160 -0.0690797258
#> gene_4585 -0.12090639 -0.0453360984 0.096929929 0.0902355529 -0.0154017838
#> gene_5718 0.06372684 0.2155799726 0.027962346 0.0324880861 0.0092146922
#> gene_79 0.08056420 -0.0689783879 0.003351939 -0.0231730415 -0.1561287730
#> gene_6660 -0.11473695 0.0999327695 0.102329913 -0.1400329905 -0.1207527026
#> gene_4803 -0.10382626 0.1191290532 -0.013400608 0.0041619312 -0.1008006957
#> gene_1621 -0.09372383 -0.0012389606 -0.134297837 -0.0148635981 -0.0230885323
#> gene_2065 -0.08572424 0.1713544037 -0.024543227 -0.0407141521 0.0048520027
#> gene_5055 0.13094447 -0.0131465597 0.009826351 -0.0581363961 -0.0406200950
#> gene_119 0.07981840 0.0681731355 0.202703509 -0.2463427394 -0.0245668964
#> gene_6256 -0.09113090 0.0311726802 0.090669227 -0.0406432197 0.1179161927
#> gene_1235 0.10009139 0.1088769640 -0.106798520 0.0451589444 -0.1164565860
#> gene_5764 -0.09892508 -0.0590311762 0.051652498 -0.0020432554 0.1182718798
#> gene_6825 0.10599278 -0.0363349080 0.165430600 -0.0529183465 0.0325786473
#> gene_185 -0.09585505 -0.2027532508 0.067755815 0.0411895171 -0.0265527749
#> gene_5691 0.06201806 0.0585208820 0.132004150 0.1719016367 0.0238516273
#> gene_2756 -0.09812838 -0.1388474860 0.043785374 -0.0763785380 0.1319330947
#> gene_941 -0.09731906 0.1980743194 -0.011887645 0.0318882952 0.1019497426
#> gene_3471 -0.09144499 -0.0565228236 -0.127642868 -0.0964617379 0.1524315969
#> gene_2028 0.09462424 -0.0408279243 0.037574696 0.0538904823 0.1212506934
#> gene_2158 -0.09155225 -0.1156918236 0.016584224 -0.0051590839 0.0396500054
#> gene_1384 0.10049992 0.1052490083 0.017071207 0.1556095219 0.0516556684
#> gene_3406 -0.09872310 -0.1310908957 -0.128724010 -0.1425119054 -0.0201489104
#> gene_3018 -0.09797907 0.1311017977 -0.006749155 -0.0318333192 -0.0866721374
#> gene_4575 -0.11914562 -0.0197361827 0.087773448 0.1733081289 0.1053616136
#> gene_4172 0.08525242 0.0819333663 0.120212515 0.0995982956 0.2056146403
#> gene_3672 -0.12324947 -0.0607443633 0.126957929 -0.0800332919 -0.0037181409
#> gene_1188 0.08600777 0.0961931254 0.114217443 0.1356990497 0.1167338859
#> gene_6557 0.09608604 0.1863496282 -0.064807090 0.0003132165 0.0788320712
#> gene_5907 -0.04473849 -0.0260392698 -0.157627984 0.0186127665 -0.0782778358
#> gene_6651 -0.05703075 0.0770912901 -0.046680885 -0.1366699937 -0.1903635218
#> gene_221 0.10541299 -0.1726180191 0.164761056 -0.1509372666 0.0006507132
#> gene_6016 -0.13331099 0.0036986632 -0.016570527 0.1304669986 -0.0361287993
#> gene_1930 -0.06402725 -0.0671097900 0.002911192 -0.1311616243 -0.0591028599
#> gene_1675 -0.05758570 0.0720895962 -0.138673360 -0.2139762849 -0.0212966071
#> gene_1284 -0.11860324 0.0341384982 0.165543504 -0.0576474260 0.0696074494
#> gene_3416 -0.09265197 -0.0774955284 0.113995205 0.0096004575 0.0085523136
#> gene_4720 -0.10404391 0.0099313425 -0.037144010 0.0554877953 -0.0628256778
#> gene_1449 -0.10868856 0.0387239826 0.011659856 0.0228699606 0.0328207210
#> gene_4760 -0.10560049 -0.1085421783 0.147350066 0.1592688136 -0.0956833947
#> gene_6903 -0.11704838 -0.0700780910 0.052415667 -0.1444546921 0.0695637912
#> gene_5141 -0.09419320 -0.1222346375 0.061725308 0.1338120747 0.0286112454
#> gene_92 0.11067614 -0.0437408487 0.059670971 -0.1686614430 -0.1958298121
#> gene_2 0.08883644 0.0098741249 0.005394240 -0.1833376408 -0.2466595240
#> gene_2480 -0.07292487 -0.0438693546 0.174208898 0.0065987955 -0.1076213753
#> gene_4417 0.08399206 0.1070208814 -0.023700831 -0.0843253941 -0.0471352334
#> gene_5327 -0.08231569 -0.0894598444 0.102556340 0.0973284855 -0.0769703908
#> gene_3751 -0.11170511 0.0174410013 0.110875306 -0.0947272510 -0.1091657350
#> gene_860 -0.08662326 -0.0200484284 -0.025535829 -0.0750039277 -0.1620452594
#> gene_1872 0.08371894 0.0017537832 0.097596101 0.1079095606 -0.0851414803
#> gene_4276 -0.06884998 0.0054996762 0.068867178 0.0676211003 -0.0257461475
#> gene_858 0.05863819 0.2046220051 -0.016558117 -0.0811289136 0.0536637994
#> gene_1060 -0.08694977 0.0863731395 0.057031245 -0.1086493825 -0.0115096153
#> gene_3214 0.09479305 0.0042495626 -0.145525299 0.0356968857 0.1573347420
#> gene_2378 -0.09431271 -0.0455995090 0.130939128 0.0193011814 0.0267202522
#> gene_3607 -0.09511772 -0.0335708329 0.075342451 -0.1351608996 0.1109631988
#> gene_130 0.07580822 -0.1076613833 0.200110490 -0.1335599042 0.0320446934
#> gene_4413 0.08943859 0.0139488805 0.143580804 0.1779023043 0.0361422712
#> gene_803 0.08115222 -0.1112449412 0.012098425 0.0602699154 -0.1711624610
#> gene_4099 -0.07034149 0.0849635449 -0.067204474 -0.1581298765 0.1204350282
#> gene_2923 -0.10519600 0.0933455151 0.214544166 0.0455167269 -0.1362494594
#> gene_6775 -0.11553468 -0.0677921116 0.009344205 0.1118315237 0.1041065285
#> gene_6040 0.10155590 0.0517459341 -0.082692302 -0.0082777055 0.2273596181
#> gene_3191 0.09216325 -0.0802898186 -0.054269339 0.0138588907 0.1180788782
#> gene_1746 -0.10744730 0.1036385351 0.090660782 0.0466650016 0.0816406226
#> gene_3148 0.10502598 -0.1883483397 0.011882675 0.0878135409 0.0720659822
#> gene_5232 -0.09852085 0.0948244807 0.091719990 -0.0513011208 0.1502984348
#> gene_5696 -0.11773376 0.1326350729 0.047039926 0.0879419357 0.0530705959
#> gene_6211 -0.08105340 -0.0022420716 -0.055058213 -0.0534348465 0.2141178206
#> gene_5360 -0.06798865 0.0443421090 0.184663319 0.0383649020 0.0257935797
#> gene_6221 -0.06265447 0.1295052587 0.202931517 0.0179250474 -0.0614654414
#> gene_226 0.07804323 -0.0549659369 0.035967960 -0.0376312370 0.1716454390
#> gene_2564 -0.10478557 0.0776000599 0.039292567 0.0882422839 -0.2199552264
#> gene_123 0.05212435 0.1307547873 0.239052165 -0.1405639195 0.1564980253
#> gene_3603 0.07381592 0.0096130180 0.116469189 0.1036249909 -0.0824012760
#> gene_195 -0.09323274 0.1741210697 -0.009620442 0.0965647143 0.0006889998
#> gene_2600 -0.08091955 -0.0702721709 0.021389790 0.0590893021 -0.1620455454
#> gene_1866 0.08618075 0.0452696437 0.181557504 0.1047633219 -0.0269560531
#> PC6 PC7 PC8 PC9 PC10
#> value -0.011584118 0.041902783 0.062525525 8.171377e-02 0.089442220
#> gene_132 -0.026517601 -0.023160588 -0.112417999 -8.520559e-02 -0.174314568
#> gene_1475 0.034067938 -0.036542370 0.071406910 2.158351e-02 -0.021598755
#> gene_6915 0.028437391 -0.013093700 0.040886549 -4.995933e-02 -0.158305792
#> gene_117 -0.060681822 -0.129695022 -0.001458957 1.157174e-02 0.016440309
#> gene_3068 0.011751815 -0.054912402 0.072706586 -3.642390e-02 -0.219960957
#> gene_2046 0.028615720 0.033930694 -0.193667727 -1.554005e-01 -0.130409450
#> gene_452 -0.110110227 -0.028797697 0.076565840 8.883033e-02 -0.019114692
#> gene_6962 0.043286530 -0.066331724 -0.036913507 6.995904e-03 0.091417304
#> gene_2773 0.110549837 0.157177881 -0.004816474 8.413171e-02 -0.027721137
#> gene_5886 -0.066033240 -0.063994520 -0.026866139 -7.064265e-02 -0.148651045
#> gene_121 -0.067146321 -0.089223141 -0.011610150 -2.871209e-02 0.007102029
#> gene_4016 0.001520939 -0.038448176 -0.126120801 -7.566070e-02 0.106224812
#> gene_4373 -0.016660734 -0.062908646 -0.115662594 3.696039e-02 0.089009589
#> gene_1194 0.109369631 -0.114464350 0.027487384 -5.319474e-02 -0.107431025
#> gene_1933 0.111518015 -0.064709800 0.198483154 -3.286100e-02 0.101771597
#> gene_4843 -0.036959399 -0.007404062 0.158625035 -4.723153e-02 0.050555855
#> gene_3400 -0.030791316 -0.084551395 -0.129528605 -1.076960e-01 -0.151655376
#> gene_4643 -0.028210501 0.013503638 -0.052879112 -9.707482e-02 0.112421830
#> gene_6708 -0.107636055 -0.039863824 -0.038062899 -3.891028e-02 -0.156739025
#> gene_6086 0.025928542 0.144260450 -0.224094877 9.112992e-02 0.122319038
#> gene_6341 0.146408592 -0.212495156 0.073758847 1.711059e-01 -0.005479361
#> gene_4213 -0.008953604 0.097336939 0.087137865 -1.426610e-01 0.010754501
#> gene_4582 0.120672513 -0.057810464 0.002457800 -2.495295e-01 0.065845141
#> gene_4585 -0.043494487 -0.098324059 -0.097627328 -5.241566e-02 0.081114061
#> gene_5718 0.072640085 -0.120256220 -0.022490665 -5.949464e-02 0.006823829
#> gene_79 0.206560950 0.022101484 -0.021204612 -2.706866e-01 0.096321491
#> gene_6660 0.094715459 0.095525074 -0.022381757 -1.005686e-01 -0.090878787
#> gene_4803 0.116787884 0.105339310 -0.136983746 1.093899e-01 0.036915418
#> gene_1621 -0.200377874 -0.165400953 -0.093148495 -9.179807e-02 -0.087020501
#> gene_2065 -0.009291028 -0.094003045 -0.093588317 8.030012e-02 0.219087010
#> gene_5055 -0.002962432 -0.090111267 0.053354251 -1.102775e-01 -0.053907573
#> gene_119 -0.052642590 -0.023139974 -0.042117145 -6.137519e-03 -0.001393991
#> gene_6256 0.018532201 -0.088176404 0.051666352 1.506292e-01 0.070020018
#> gene_1235 0.016782811 -0.151182980 -0.047305392 8.816540e-02 0.100119023
#> gene_5764 -0.044685707 0.067865841 -0.039975899 9.971297e-02 -0.022249594
#> gene_6825 -0.023045970 0.015638812 -0.014636547 3.251909e-02 -0.018758772
#> gene_185 0.059991063 -0.193433690 -0.013825707 -1.689575e-02 0.117527534
#> gene_5691 -0.100092768 0.004810522 -0.195267347 -6.357705e-02 0.057791633
#> gene_2756 -0.015089574 -0.118978688 -0.046253415 -4.437187e-02 -0.085416261
#> gene_941 -0.089540306 -0.047468289 -0.080354985 3.521052e-03 0.009564774
#> gene_3471 -0.192763535 0.112348063 -0.078888167 -9.901510e-02 -0.013974971
#> gene_2028 -0.007913866 0.029211726 -0.032339394 1.321827e-01 0.090138785
#> gene_2158 0.099411249 -0.047003334 0.130204029 -1.396588e-01 -0.066062363
#> gene_1384 0.039606148 0.047188719 -0.055638164 3.764576e-02 0.047106781
#> gene_3406 -0.111167109 0.035513703 -0.159432272 -1.068359e-01 -0.031713922
#> gene_3018 0.011566997 -0.165255013 0.073144873 6.288531e-02 -0.016066725
#> gene_4575 -0.130207018 -0.124361746 -0.052458183 -3.498275e-02 0.071862630
#> gene_4172 0.097890703 -0.082962365 0.097311561 -1.560055e-02 0.055453755
#> gene_3672 0.014319873 -0.222075319 0.056511765 -1.260637e-01 -0.078983397
#> gene_1188 -0.068788941 -0.165323548 -0.135134508 3.689071e-02 0.007527359
#> gene_6557 -0.015563587 0.171069251 -0.141080065 -4.781518e-02 0.015551979
#> gene_5907 -0.258564556 0.030759140 0.239210764 1.475092e-01 -0.114950511
#> gene_6651 0.209228178 0.049278826 -0.062829736 1.898772e-01 0.066911595
#> gene_221 0.009312017 -0.021860148 -0.019879437 7.234249e-02 -0.002191888
#> gene_6016 -0.031815533 -0.041612832 -0.093962566 2.371567e-02 -0.103573939
#> gene_1930 -0.031226095 -0.115145479 0.090601664 1.209940e-01 0.046143572
#> gene_1675 -0.086875783 -0.003825691 0.050289227 -8.247028e-02 -0.114735036
#> gene_1284 0.119107526 0.070414203 -0.046685397 2.996119e-02 0.043081422
#> gene_3416 -0.163063311 0.179629279 -0.022790643 9.452288e-02 -0.034211179
#> gene_4720 -0.103785600 0.196703271 0.083977156 -1.064463e-01 -0.042401627
#> gene_1449 -0.038195737 0.012314243 -0.138163368 2.219561e-01 -0.213258261
#> gene_4760 -0.132680834 -0.006598336 0.041915303 -3.354228e-02 0.032610722
#> gene_6903 0.058894023 0.046524212 -0.165916554 -9.376301e-03 -0.067511975
#> gene_5141 0.159347695 -0.189484139 -0.018762697 9.552430e-02 0.056490404
#> gene_92 -0.057053214 0.136587310 -0.017751288 -4.082594e-02 0.044622644
#> gene_2 0.032264667 0.029658586 0.091528628 6.079940e-02 0.051334018
#> gene_2480 0.088866672 0.104972057 0.021529073 -3.156340e-03 -0.094160255
#> gene_4417 0.158554310 -0.104482106 -0.025994853 -1.891487e-01 0.061121710
#> gene_5327 0.169313864 -0.006593499 0.051844310 1.251984e-01 -0.175343139
#> gene_3751 0.108057787 0.048266471 -0.021449518 -7.978463e-03 -0.064249512
#> gene_860 -0.009260906 -0.212049766 0.074344089 3.362043e-02 0.132893001
#> gene_1872 0.014346895 0.133202425 0.025861757 -5.224829e-02 -0.164428017
#> gene_4276 -0.007906535 0.082155848 -0.065091818 1.858336e-01 0.086537757
#> gene_858 0.155568836 -0.065057234 -0.078086778 7.036293e-02 -0.152285918
#> gene_1060 -0.154427518 0.010840173 0.054387403 1.316743e-02 -0.269224221
#> gene_3214 0.102761486 0.080859834 -0.089164543 7.470961e-02 -0.143448643
#> gene_2378 -0.031812751 0.047798606 0.140672666 -2.841856e-01 0.143578596
#> gene_3607 0.080173655 0.233304213 -0.080664833 9.375455e-05 0.023440488
#> gene_130 -0.069800753 -0.135493551 -0.045926392 4.841911e-02 -0.075768985
#> gene_4413 -0.124141474 0.035204825 0.072974553 1.020811e-01 0.040573225
#> gene_803 0.131905696 -0.028806663 -0.096082579 1.583371e-02 -0.127964077
#> gene_4099 -0.093949394 0.037483805 -0.072111609 -4.946848e-02 0.188963411
#> gene_2923 0.027955151 0.052442640 -0.115272054 -1.197007e-01 0.047883347
#> gene_6775 0.098714180 -0.111786910 -0.072227889 -2.336802e-03 -0.090176676
#> gene_6040 0.164385492 0.063509885 0.082558620 -1.016271e-01 0.058509420
#> gene_3191 0.156897809 0.058762901 0.229890649 9.565277e-04 -0.067033239
#> gene_1746 0.163407636 0.022899310 0.140094299 -7.728043e-02 -0.177058677
#> gene_3148 -0.028714996 0.123178849 0.004415169 6.561825e-02 0.096906442
#> gene_5232 0.066738513 0.066374752 0.165917222 -8.016000e-02 0.066728598
#> gene_5696 -0.034066658 -0.079133963 0.093738682 -5.490209e-02 -0.166020332
#> gene_6211 0.113067449 0.022906611 -0.109809102 -1.145359e-01 -0.033518268
#> gene_5360 -0.054250752 0.184088838 0.275015586 -3.179360e-02 0.072618704
#> gene_6221 0.055663516 0.079864641 0.106310976 6.987919e-02 0.074206163
#> gene_226 0.193818561 0.099230326 -0.009050166 1.217980e-01 -0.173104058
#> gene_2564 0.036374381 0.105920181 -0.015526526 8.907211e-02 0.028691640
#> gene_123 -0.042385598 -0.038816275 -0.053131673 1.199978e-01 -0.061023215
#> gene_3603 -0.116721588 0.067865309 0.090051416 -1.332344e-03 -0.117321500
#> gene_195 0.086139096 0.122060179 -0.121196848 -1.841547e-01 0.019823407
#> gene_2600 0.192937898 -0.020137142 -0.166120203 5.034278e-02 -0.066724487
#> gene_1866 -0.156792864 -0.028777942 -0.122224925 -1.208228e-01 0.009533058
#> PC11 PC12 PC13 PC14 PC15
#> value -0.0505681904 -0.029672975 -0.023044344 -8.671848e-02 -1.110277e-02
#> gene_132 0.0357826277 0.063559671 -0.062864742 -3.601575e-02 9.334215e-02
#> gene_1475 -0.1161144460 -0.059494100 0.049526727 8.527445e-02 -9.713246e-04
#> gene_6915 -0.0659867000 0.050148185 0.151587379 -3.350916e-02 -1.975809e-02
#> gene_117 0.0994254698 -0.070617014 0.015933722 -4.860748e-02 -2.925908e-02
#> gene_3068 -0.0263341072 -0.056795786 -0.033392990 -6.185896e-02 -3.645897e-02
#> gene_2046 -0.0128242703 0.108457765 -0.128962617 -4.387722e-03 1.733662e-01
#> gene_452 0.1901749653 -0.057121149 -0.230275525 7.705298e-02 2.094529e-01
#> gene_6962 0.0250610765 -0.143668609 0.040484867 -9.937884e-02 2.344835e-02
#> gene_2773 0.0115337998 0.014298397 -0.020146903 -1.149864e-01 1.856460e-02
#> gene_5886 0.0463770971 0.144767330 0.045297785 -5.106893e-02 -1.529677e-01
#> gene_121 0.0895952229 -0.105721129 0.017769564 -1.566989e-02 -1.031384e-01
#> gene_4016 -0.0938127314 0.060513374 0.015536237 2.484938e-04 6.168431e-03
#> gene_4373 -0.0352518114 -0.027192839 -0.213380656 -5.563364e-02 4.177683e-02
#> gene_1194 -0.1511501701 -0.136368472 -0.149366274 3.210417e-01 -1.131127e-01
#> gene_1933 0.1142349051 0.121420683 -0.081157226 -4.580741e-02 -1.271927e-01
#> gene_4843 -0.1168261180 -0.034599598 -0.097825976 -6.824396e-02 2.615740e-01
#> gene_3400 -0.0504941968 -0.148285357 0.044065559 1.958397e-01 1.847276e-03
#> gene_4643 0.0346901036 -0.012068222 -0.110991135 -2.012080e-02 -8.918250e-04
#> gene_6708 0.0839026371 0.170855774 0.049454205 4.070124e-02 3.320018e-02
#> gene_6086 -0.0452254037 -0.058087425 -0.115846985 -1.565754e-01 2.653992e-04
#> gene_6341 -0.0972544244 -0.040754861 0.053187418 -3.307303e-02 5.012608e-02
#> gene_4213 0.1329883040 -0.046209334 -0.084593619 2.570309e-02 -4.642960e-02
#> gene_4582 -0.0397964142 -0.042612671 -0.012123796 3.546087e-02 -7.080992e-02
#> gene_4585 -0.1685656183 0.108248888 -0.110892512 6.997614e-05 -8.103245e-03
#> gene_5718 0.0008852634 -0.090581500 0.158340217 -1.066911e-01 6.392656e-02
#> gene_79 -0.0326399368 0.140689413 0.066772111 -8.799780e-02 -8.954722e-02
#> gene_6660 -0.0255342767 -0.005534855 0.071953347 1.471758e-01 -9.584503e-03
#> gene_4803 -0.0545556425 0.159800535 0.103083520 -1.374674e-01 1.005023e-04
#> gene_1621 -0.1368327859 0.137262931 -0.011747784 1.188145e-02 -9.443625e-03
#> gene_2065 0.1962385757 0.025311607 -0.029729200 3.470247e-03 -4.837424e-02
#> gene_5055 -0.1546560928 -0.131871730 -0.086975711 -6.068029e-03 9.979978e-02
#> gene_119 0.0220198342 -0.134139004 0.046406739 1.039614e-02 -4.995765e-02
#> gene_6256 0.0040762800 0.174647004 0.225911616 1.243446e-01 3.741730e-02
#> gene_1235 -0.1291073091 -0.031458020 -0.079110900 5.700427e-02 1.088337e-01
#> gene_5764 -0.1587970743 -0.069598751 -0.055385953 -1.667405e-01 2.247525e-01
#> gene_6825 -0.2010391999 -0.074393333 -0.110874758 -1.164024e-01 -3.983128e-02
#> gene_185 0.0010438826 -0.063190076 0.135001722 -4.702548e-02 9.893405e-02
#> gene_5691 -0.0044445482 0.137685868 0.038878508 -6.971771e-03 -1.997286e-01
#> gene_2756 0.1981920234 0.133892448 0.041884460 5.177458e-02 -1.704164e-02
#> gene_941 -0.0213947249 0.071693020 -0.194487985 -1.616621e-01 1.644190e-02
#> gene_3471 0.0654051645 -0.006520384 0.061806985 5.656109e-02 6.025017e-02
#> gene_2028 -0.1777762807 -0.057586697 0.200850532 3.038319e-01 1.017272e-01
#> gene_2158 0.0576899880 -0.006768007 -0.145345903 -2.888973e-02 2.169164e-01
#> gene_1384 0.1299847234 0.063282636 -0.083190395 -1.381932e-01 1.726499e-01
#> gene_3406 -0.0386860066 -0.002375086 -0.114397244 7.406050e-02 -5.582141e-02
#> gene_3018 0.0260429165 -0.190688874 0.033307502 -2.489759e-01 -5.823696e-02
#> gene_4575 -0.0114223145 0.100423040 -0.023556594 7.542994e-03 -8.846413e-02
#> gene_4172 -0.1125167193 0.017131850 0.145085926 -8.414454e-02 -4.059013e-02
#> gene_3672 0.0706949767 0.060076364 0.067236546 9.595469e-02 1.298691e-01
#> gene_1188 -0.0365447810 0.099005854 0.043196685 -8.251686e-02 1.252252e-01
#> gene_6557 -0.0069841020 0.029078491 0.107717298 -5.446581e-02 -5.157621e-02
#> gene_5907 0.0118700805 0.051598397 -0.001748227 -2.431703e-02 1.218615e-02
#> gene_6651 0.0358583779 -0.025594735 -0.108194008 -3.619644e-02 -6.257973e-02
#> gene_221 0.0488815928 -0.034480629 0.092312203 -1.086879e-01 -7.202455e-05
#> gene_6016 0.1712490304 0.019901589 -0.136465154 -4.341266e-02 -4.296402e-03
#> gene_1930 -0.2012306815 0.156939026 -0.238396404 -2.838465e-02 -2.695084e-01
#> gene_1675 -0.1233386500 -0.032826831 0.171138367 -1.916444e-01 -7.838382e-02
#> gene_1284 0.1069451058 -0.063914321 -0.170575432 1.252140e-01 -8.107094e-02
#> gene_3416 -0.2313031612 -0.057602994 0.059520832 -2.718066e-02 -1.026099e-01
#> gene_4720 0.1302290710 -0.069613388 0.135896636 1.635884e-01 -1.143562e-01
#> gene_1449 0.0364991809 -0.013510080 0.141311674 8.787936e-02 6.832821e-02
#> gene_4760 0.0219412439 0.033061623 -0.056012029 2.368530e-02 -9.523304e-02
#> gene_6903 -0.0217172450 0.040676079 0.038701691 9.796641e-02 -1.933362e-02
#> gene_5141 0.0071363895 0.080620186 0.051385320 -2.871751e-02 -1.545634e-02
#> gene_92 0.1734322652 0.052210499 0.003380110 -7.536817e-02 8.379978e-02
#> gene_2 0.1065749946 0.063450542 -0.011105383 6.108482e-02 1.303958e-01
#> gene_2480 0.0323095547 -0.135333807 0.060624833 -4.270298e-02 -4.618591e-02
#> gene_4417 -0.1093256595 0.216340801 -0.067274467 8.014640e-02 1.340287e-01
#> gene_5327 0.1067981006 0.041531212 -0.113851078 6.103137e-02 3.479383e-02
#> gene_3751 -0.1488694793 0.156903740 -0.057201069 8.702957e-02 9.129481e-02
#> gene_860 0.0069795746 0.056987542 0.133944610 1.302561e-01 1.429195e-01
#> gene_1872 -0.0311195748 0.282190605 0.032172084 -3.922886e-03 1.653121e-01
#> gene_4276 0.0503776269 0.157626713 -0.046060133 1.795528e-01 -1.837357e-01
#> gene_858 0.0338383063 0.045497075 -0.174999909 1.246323e-01 1.279192e-02
#> gene_1060 -0.0376671374 -0.160979173 -0.123402020 -5.740402e-02 1.316188e-01
#> gene_3214 0.0222877986 -0.138546601 0.060612723 -1.542462e-02 -5.446756e-02
#> gene_2378 0.0959828318 -0.218232424 -0.040662731 6.596964e-02 -1.836029e-02
#> gene_3607 -0.0894617709 -0.017932040 -0.068215939 1.817731e-01 5.005008e-02
#> gene_130 0.0999479440 0.125714719 -0.008156970 -3.558522e-02 -7.025498e-02
#> gene_4413 0.0305609927 -0.089815257 0.036776606 8.437043e-02 8.924242e-03
#> gene_803 -0.0251554942 -0.035271853 0.125044159 -4.040051e-02 -1.668713e-01
#> gene_4099 0.0701463430 0.050190292 0.187914101 -1.094976e-02 1.772421e-01
#> gene_2923 -0.0416301194 0.004340718 -0.048943191 -1.321117e-02 -4.963242e-03
#> gene_6775 0.2434008640 -0.119510955 -0.032734025 4.023934e-02 -1.737409e-02
#> gene_6040 -0.0531889792 0.006548546 0.042592045 -1.817000e-02 -5.167293e-03
#> gene_3191 0.1128721449 0.197841907 -0.052320646 -7.402952e-02 -1.270115e-01
#> gene_1746 -0.1765219346 0.001162695 -0.003597823 -3.316806e-02 -9.698180e-02
#> gene_3148 0.0496369658 -0.028432517 -0.071363048 3.091782e-02 1.468168e-01
#> gene_5232 0.0090006012 0.026193137 0.093253094 3.272283e-02 7.026024e-02
#> gene_5696 0.0463606126 0.010132471 0.098345413 -3.859337e-02 6.078510e-02
#> gene_6211 0.0056805872 0.010399754 -0.102791951 -8.105943e-02 5.699437e-03
#> gene_5360 0.0379132476 0.143466982 -0.015426613 -1.228934e-01 -7.131315e-02
#> gene_6221 -0.1961411963 -0.002819828 -0.016959153 1.823968e-02 1.458991e-01
#> gene_226 -0.0427785515 -0.021398111 0.008140725 -7.093943e-02 -1.155793e-03
#> gene_2564 -0.0333292320 0.078059411 0.105326567 9.258189e-02 1.355532e-01
#> gene_123 0.0787030621 0.056523763 0.017019200 8.959918e-02 -3.222191e-02
#> gene_3603 -0.0507540785 0.238531916 0.022452119 -1.186661e-01 8.346769e-02
#> gene_195 0.0630753659 -0.028563282 0.111473498 -1.231810e-02 1.278742e-01
#> gene_2600 0.1500586977 -0.084035781 0.135964604 -2.252997e-01 7.342676e-02
#> gene_1866 -0.1144799153 -0.076262364 0.034086095 -1.517431e-01 -6.521611e-02
#> PC16 PC17 PC18 PC19 PC20
#> value -2.299399e-01 -0.004752893 -0.0397217890 0.1007577395 -0.040678630
#> gene_132 3.255715e-02 -0.153957159 0.1970507306 -0.0961104712 0.004171639
#> gene_1475 -6.960937e-02 0.183083841 0.0259080866 0.0348791224 0.045435516
#> gene_6915 -3.204542e-02 0.059694148 0.0223964204 -0.1538938763 -0.055166243
#> gene_117 -3.739124e-03 0.111873780 -0.0546572692 -0.0320682956 0.013680914
#> gene_3068 3.897978e-02 -0.017823710 0.0021961010 0.0952519322 0.027075306
#> gene_2046 1.170946e-02 -0.016747261 -0.1440866916 0.0338640059 0.025949346
#> gene_452 -4.747908e-02 -0.138671309 0.0448147782 -0.1255413668 0.003905417
#> gene_6962 1.422414e-01 -0.030173966 -0.0106139742 0.0413894983 -0.261108485
#> gene_2773 -1.747613e-02 0.074601205 0.0539139638 0.0542296861 0.051785321
#> gene_5886 -1.575036e-01 -0.143714588 0.0266737575 0.1109680319 -0.085832895
#> gene_121 -1.862451e-03 0.119538844 -0.0963326637 0.0349775569 -0.042300606
#> gene_4016 -3.404015e-01 0.034828837 0.2180697374 0.1093882310 0.125202198
#> gene_4373 -5.955265e-02 -0.041513816 -0.1269364426 -0.0619486779 0.132283992
#> gene_1194 -1.121050e-01 0.031972738 0.0732149109 -0.0415969583 0.039993376
#> gene_1933 2.269796e-01 0.041682192 -0.0193080096 0.0523253184 -0.068294928
#> gene_4843 9.350551e-02 0.013752510 0.0822622652 -0.0763827070 0.135698880
#> gene_3400 1.091101e-02 -0.100309706 0.0622247202 0.3152589320 0.168795542
#> gene_4643 3.195487e-02 -0.031621619 0.0863155919 0.2523365385 -0.058246724
#> gene_6708 6.853507e-02 0.133323941 0.2473154617 0.0319825247 0.108424714
#> gene_6086 -5.095938e-02 -0.110658131 0.0713466076 -0.0837049888 0.022782902
#> gene_6341 1.174342e-01 -0.097171485 0.0048893175 0.0358403230 -0.019949565
#> gene_4213 -1.128627e-01 0.016020886 -0.1513856401 0.0172433946 0.053804597
#> gene_4582 8.697533e-02 -0.025097626 0.0347144512 0.1039244215 -0.020852384
#> gene_4585 -7.599956e-03 -0.175295789 -0.0140251726 -0.1368691351 0.007232043
#> gene_5718 7.776410e-02 0.023247306 0.1725421152 -0.1080203369 0.126546363
#> gene_79 -5.519510e-03 -0.031950367 0.0128373172 -0.0794250638 -0.003985277
#> gene_6660 -3.767302e-02 0.064813254 0.1137601037 0.0193023561 0.099384297
#> gene_4803 2.348659e-02 -0.052056713 0.0765171799 0.0526726353 -0.013331744
#> gene_1621 -9.613315e-02 -0.132557693 -0.1082209132 -0.0153330680 -0.103735677
#> gene_2065 -1.445099e-01 -0.092772446 0.0249447630 -0.0677458611 0.144522594
#> gene_5055 -2.802258e-01 0.034903740 -0.0410437663 -0.1146525421 -0.100157609
#> gene_119 -2.120518e-02 0.109727092 -0.0895327646 -0.0051246324 -0.011168824
#> gene_6256 -1.168966e-01 -0.170413864 0.0458325861 0.0190919656 -0.305191521
#> gene_1235 -4.714985e-02 -0.062634158 -0.1402375141 -0.0650346620 0.149110635
#> gene_5764 7.316979e-02 0.166705596 -0.1457404441 -0.0226586696 0.109851738
#> gene_6825 1.939801e-05 -0.103662880 0.1265385807 -0.1160618054 -0.028701959
#> gene_185 -8.338585e-03 0.140613914 -0.0264690387 -0.0304568892 -0.086384393
#> gene_5691 1.498355e-02 -0.041094232 -0.0760570749 -0.0262687876 0.053958081
#> gene_2756 -1.048875e-01 -0.052553649 -0.0642793248 -0.0497514495 0.155165915
#> gene_941 8.154689e-02 -0.100601242 0.0570674919 -0.0578561164 -0.048770214
#> gene_3471 1.097648e-01 -0.046612743 0.0414598623 0.1056301996 -0.216433436
#> gene_2028 6.119285e-02 -0.029919660 -0.0726232380 -0.0719186330 -0.097436435
#> gene_2158 -1.993422e-02 0.032030120 -0.2175637583 0.1719952734 -0.051623384
#> gene_1384 -8.233340e-02 0.115484899 0.0355936147 -0.0624312591 -0.047598060
#> gene_3406 3.501537e-02 0.056494095 0.1310169751 -0.0650826996 -0.107594732
#> gene_3018 1.184873e-01 0.078184900 0.1474238880 -0.1930885126 -0.147568988
#> gene_4575 1.701143e-02 0.085344165 -0.0423245785 0.0773157811 -0.108605798
#> gene_4172 5.588660e-02 0.024025587 0.0052012196 0.0197195850 0.068177272
#> gene_3672 -4.145561e-02 -0.082739162 0.0470000963 -0.0738443245 0.044529537
#> gene_1188 -8.530568e-02 0.106570855 0.0276290510 0.1054408104 0.073022235
#> gene_6557 -2.702775e-02 -0.036889808 -0.0754299752 0.0868551107 -0.070177543
#> gene_5907 -8.230602e-02 -0.032586490 0.0536540258 0.0458687982 0.049283076
#> gene_6651 -6.766714e-02 0.047679486 -0.0116668911 0.0944087945 0.144469376
#> gene_221 4.279574e-02 0.005701482 -0.0406588149 -0.0213176879 -0.038411938
#> gene_6016 2.663450e-01 0.032071086 -0.0028345918 0.0684065043 -0.007422101
#> gene_1930 4.625509e-02 0.148838535 -0.1188597461 0.0996114141 -0.007510669
#> gene_1675 -4.673228e-02 0.043178560 -0.0298753988 0.0140523387 -0.007934691
#> gene_1284 5.491361e-02 0.033522033 -0.0554921487 -0.0044591025 -0.133778335
#> gene_3416 1.354877e-01 0.025792332 0.0880231773 -0.0558829851 0.107398516
#> gene_4720 6.977714e-02 0.213471313 -0.0365548903 -0.1100654033 0.106415632
#> gene_1449 5.085295e-02 0.079621970 -0.1852916728 0.0796785441 0.069490080
#> gene_4760 -9.309959e-02 0.079931207 0.0129627516 -0.0561724490 0.138155356
#> gene_6903 1.057729e-01 -0.196061809 -0.0739343576 -0.1758633755 0.110823228
#> gene_5141 6.784891e-03 0.105040122 0.0302103904 0.1012938487 0.149202994
#> gene_92 2.589569e-02 0.013520048 0.0387950308 0.1033030531 0.026088658
#> gene_2 1.408106e-02 0.101812429 -0.0268132123 0.0159853076 0.020819961
#> gene_2480 -1.861720e-01 -0.303725858 -0.1139316119 0.1186249816 -0.076329591
#> gene_4417 4.148733e-02 0.229419082 0.1418109780 0.0955758935 -0.055080691
#> gene_5327 -9.203262e-02 -0.085845753 0.0859539881 0.1142118492 -0.071213702
#> gene_3751 1.956283e-01 -0.104304193 -0.0478105313 -0.1353936471 -0.012135711
#> gene_860 4.806277e-02 -0.119047396 -0.1734748860 -0.1308131640 -0.002361332
#> gene_1872 -1.395597e-01 0.129221105 0.0231687011 -0.1633867378 -0.080005773
#> gene_4276 -1.930258e-01 0.231770846 0.0017473651 -0.1855602038 -0.241087189
#> gene_858 1.662601e-01 0.004735457 0.0513598491 0.0870091589 -0.077324021
#> gene_1060 -7.443897e-02 0.068074869 0.0776024732 0.0370158197 -0.222975145
#> gene_3214 -1.597250e-01 -0.007927715 -0.0279366209 -0.0464524608 0.122335779
#> gene_2378 5.283049e-02 -0.087188125 -0.0642113767 -0.0817988677 0.025591201
#> gene_3607 1.713906e-01 0.017777294 -0.0911568567 -0.0395482121 0.079143247
#> gene_130 1.813357e-02 0.052959978 -0.0005080529 0.0700526496 -0.015907637
#> gene_4413 4.569822e-02 -0.076484606 0.0688086161 0.0313180535 -0.189690312
#> gene_803 7.891069e-02 -0.018829265 -0.1535784954 0.0802319910 0.075708960
#> gene_4099 3.871797e-02 -0.029946366 0.0107356079 0.1770253763 0.074838849
#> gene_2923 1.814348e-02 -0.066009533 0.0764782542 0.0276158206 -0.090804522
#> gene_6775 -6.170171e-02 0.129407348 0.0577414606 -0.1276045230 0.024609502
#> gene_6040 -8.746578e-02 0.002799003 -0.1399911329 0.0533400475 -0.143857764
#> gene_3191 6.165283e-02 -0.220274285 -0.0307877124 -0.0672897979 -0.009349966
#> gene_1746 1.185728e-02 0.080267169 0.1012947451 0.1014385571 -0.056958449
#> gene_3148 -2.855724e-02 0.012933864 0.0829320468 0.1686719607 -0.010407699
#> gene_5232 -2.141569e-02 0.018055422 0.2220823321 -0.1476480078 0.078214199
#> gene_5696 -7.649800e-03 -0.096751610 -0.2226833030 -0.0323760326 0.069918849
#> gene_6211 -9.752890e-02 0.171340640 -0.2474948700 -0.1709619857 -0.127391374
#> gene_5360 -5.730229e-02 -0.101452839 0.0073563156 0.0216365453 0.162895728
#> gene_6221 -1.102198e-01 -0.008080853 -0.0791657274 0.2460217468 -0.023605101
#> gene_226 -5.311889e-02 -0.087557494 0.0489264869 -0.1339921493 0.017045030
#> gene_2564 7.428053e-02 0.004482958 0.0710832417 -0.0062109392 -0.109569076
#> gene_123 6.013786e-02 0.020170172 -0.0287657914 0.0038160073 0.005502254
#> gene_3603 6.761760e-02 0.108490650 -0.2465374810 -0.0107941652 0.049127878
#> gene_195 -4.851389e-02 0.069016516 -0.0992287684 -0.0430747308 -0.111515270
#> gene_2600 -4.188859e-02 0.019129757 0.0264980945 0.0073999263 -0.064836428
#> gene_1866 6.721625e-02 0.008209124 -0.0360669731 -0.0003343188 -0.042249758
#> PC21 PC22 PC23 PC24 PC25
#> value 0.018388402 0.070489320 -0.1658299691 -0.0237113317 -0.076132864
#> gene_132 -0.086219294 -0.005537253 0.0474820678 0.0363504056 -0.057859042
#> gene_1475 -0.022650050 -0.173293837 0.0446260611 -0.0695432547 -0.146717954
#> gene_6915 0.177826239 -0.079011747 0.0188084297 0.0639080283 0.089637124
#> gene_117 0.038376087 -0.026296123 0.1112191412 -0.0201658909 0.013326171
#> gene_3068 -0.068739956 -0.124110385 -0.0259927485 -0.0210505588 -0.057824742
#> gene_2046 -0.027215374 -0.047151676 0.0263412695 0.0698659560 0.020083430
#> gene_452 -0.013190723 -0.038753559 0.0797660407 -0.1600900223 0.286114352
#> gene_6962 -0.008260165 0.103707176 0.0909476173 -0.1613996233 -0.051807694
#> gene_2773 -0.108836837 -0.177438194 0.0040934240 -0.0185637365 0.097789501
#> gene_5886 0.001628489 -0.080415565 0.1210685208 -0.0015972243 -0.065257861
#> gene_121 0.013978470 0.054958128 0.1043612283 0.0813646962 0.036031572
#> gene_4016 -0.091024062 -0.040246664 0.0473379906 0.0019735475 -0.002123838
#> gene_4373 -0.058048053 0.070410495 0.0201409322 0.2816091477 -0.090983395
#> gene_1194 -0.054658159 -0.042635723 -0.0938595543 0.0205957786 0.019148981
#> gene_1933 0.199790970 0.054402377 -0.0404222036 -0.1370935050 -0.053783087
#> gene_4843 0.002585352 -0.169952733 -0.0480171710 0.0093615466 0.015372669
#> gene_3400 0.002507975 0.065691914 -0.1254480522 -0.0375122740 -0.113270646
#> gene_4643 0.277994627 -0.014248981 0.0211454563 -0.0344760442 -0.130754327
#> gene_6708 0.037653322 0.102501256 0.0034644978 0.1186806199 -0.021596036
#> gene_6086 -0.000086030 -0.036486842 0.0571718794 0.0086582782 -0.009738399
#> gene_6341 -0.173578370 0.122322753 -0.0593768800 -0.1330455618 -0.124138114
#> gene_4213 0.102654654 -0.036753259 0.0864662847 0.0835076449 0.073581270
#> gene_4582 -0.004287780 0.129296504 0.2006318467 -0.1017501747 0.097641069
#> gene_4585 0.209929132 0.078054683 0.1477248751 0.1141949637 -0.101700920
#> gene_5718 -0.129227605 -0.217525688 -0.0091970714 -0.0187276285 0.126412518
#> gene_79 -0.086513682 -0.083139130 0.0332593877 -0.1018380849 0.103407695
#> gene_6660 0.058962276 0.090644764 -0.0481965256 -0.0261332578 0.108278778
#> gene_4803 -0.045480163 -0.032729941 0.1820814428 0.1862369721 -0.155583326
#> gene_1621 -0.112565533 0.029198986 0.0222629858 -0.0729618711 0.012675154
#> gene_2065 0.117013240 -0.017594901 -0.0252987010 -0.1527775010 -0.051238695
#> gene_5055 0.138553043 -0.067184084 -0.0254333138 -0.0640365597 -0.056525833
#> gene_119 0.034764026 -0.021765376 0.1343326750 0.0550616899 -0.060997102
#> gene_6256 0.078367740 -0.124053685 0.0779188095 -0.0271537405 -0.006525966
#> gene_1235 0.144332203 -0.141207701 0.0917771006 -0.1087931338 -0.033080685
#> gene_5764 -0.001506309 -0.044403219 0.2143961465 -0.0045671432 -0.020121293
#> gene_6825 -0.151652405 0.288693716 -0.0715569362 -0.0612235669 0.115192864
#> gene_185 0.046585630 -0.047512600 0.0490307844 0.0412145017 0.005622341
#> gene_5691 -0.169249349 0.018112407 0.1369800872 -0.2105987242 0.194863730
#> gene_2756 -0.128770016 0.072568411 -0.1632541445 -0.0413149288 0.061704041
#> gene_941 0.191631871 0.047851986 -0.1549263401 0.0319114876 0.052424889
#> gene_3471 -0.103095960 -0.116811451 -0.1029251825 -0.0905556762 0.032971162
#> gene_2028 0.058701373 -0.073238537 -0.2020645604 0.0252997971 0.081013064
#> gene_2158 0.112999938 0.072235114 -0.0110873474 -0.0286132722 0.158928421
#> gene_1384 -0.179225779 -0.122001163 -0.2423317184 0.0325512596 -0.190439437
#> gene_3406 -0.132590439 -0.068637253 -0.0003677196 0.0136679269 0.028231118
#> gene_3018 -0.008538153 -0.044607211 -0.0816640354 -0.1244584991 0.011171395
#> gene_4575 0.043093684 -0.113575965 0.0240486289 0.0503835409 -0.083311176
#> gene_4172 0.034965113 0.184805948 0.0373786185 0.2127011594 0.118678780
#> gene_3672 -0.077498692 -0.016449525 0.0907149857 -0.0893099040 -0.026047039
#> gene_1188 0.018224799 0.196473063 -0.0024075202 0.1387757997 0.094758448
#> gene_6557 0.032665534 -0.152841327 0.0739426294 -0.1914947624 0.014545600
#> gene_5907 0.103625982 0.108888074 -0.0702727192 0.0058452682 0.078640754
#> gene_6651 0.012708856 -0.068524154 -0.1544784620 -0.0761251113 0.083128699
#> gene_221 -0.082834117 0.096206777 -0.0004841783 -0.0653715447 -0.088840593
#> gene_6016 0.100419325 -0.142042093 -0.0587574072 -0.0262969025 0.106181710
#> gene_1930 -0.023277491 -0.025223346 -0.1559908746 0.0686449091 0.127155104
#> gene_1675 0.193388238 0.117338645 -0.0391716027 -0.0687784929 0.110116041
#> gene_1284 -0.065061453 -0.022461579 0.0283880475 0.0713792840 -0.001053296
#> gene_3416 0.070089764 0.109803862 -0.0361341171 0.0197499618 -0.105392140
#> gene_4720 -0.109982901 0.046320142 -0.0629266020 0.0296953174 -0.021199450
#> gene_1449 0.132650966 0.141026704 0.0614029067 -0.0562936184 0.118290045
#> gene_4760 0.069628285 -0.141359631 -0.0089366342 -0.0186355104 0.225818817
#> gene_6903 0.118829342 -0.052087027 -0.1007238087 0.0046375068 0.015648392
#> gene_5141 0.016442798 -0.001466986 0.0027620463 -0.1598498610 0.072796967
#> gene_92 0.112986665 0.004992620 -0.0937103422 0.0282308886 -0.037301294
#> gene_2 -0.081622082 0.156034316 0.1879429429 0.0051953476 -0.045628315
#> gene_2480 0.057876418 -0.135228536 0.0072354491 0.0576200574 0.079258111
#> gene_4417 0.032624856 0.033684918 -0.0384093961 -0.0609715117 0.055929094
#> gene_5327 -0.009729354 0.203108660 0.0079332463 -0.1476047134 -0.155628911
#> gene_3751 0.209154461 -0.068667021 -0.0769937213 0.0122387452 -0.033062451
#> gene_860 -0.167144830 0.020538232 -0.1201015099 0.0989469155 -0.011289471
#> gene_1872 0.145876406 0.099711845 -0.1276307010 0.0009476591 -0.059208782
#> gene_4276 0.018390144 0.055942186 -0.0556587295 -0.1163063940 0.033212598
#> gene_858 -0.045504527 -0.068414791 0.1055939779 0.0026140164 -0.028473414
#> gene_1060 -0.051462061 -0.009601400 0.0604314843 0.0283346130 -0.038185448
#> gene_3214 0.148030173 -0.013030018 0.1711446663 -0.1310348304 -0.022222797
#> gene_2378 0.011874425 0.015834973 -0.1338579612 0.0314442933 -0.063804796
#> gene_3607 0.019466799 0.083553211 0.0817801127 -0.1858320753 0.019903601
#> gene_130 0.029972392 -0.187562539 -0.1782433800 0.0132066653 -0.044858407
#> gene_4413 -0.001786021 -0.140185511 0.0733101929 0.2585089176 0.153852092
#> gene_803 -0.063178429 -0.133287874 -0.1321636644 0.2215035312 -0.217532026
#> gene_4099 0.022855855 -0.056613674 -0.1102208115 0.0314551286 0.158487916
#> gene_2923 -0.020013782 0.090215979 -0.1273232440 0.0507431037 0.092760464
#> gene_6775 0.110286921 0.011006070 0.0666339637 0.0178284775 -0.192331343
#> gene_6040 -0.013290155 0.088815955 0.0081441158 0.0727913252 0.055057569
#> gene_3191 -0.009941879 0.012714117 0.0113492095 0.1067345530 -0.016504789
#> gene_1746 -0.039195817 -0.117754419 0.0460896047 0.0605549392 0.139678779
#> gene_3148 -0.146239667 0.078852017 -0.0189810645 0.0030872001 0.035226959
#> gene_5232 0.150044214 -0.077301855 0.0626055574 -0.0294491836 -0.153797546
#> gene_5696 -0.128785219 0.078892885 -0.0353659065 -0.0510468849 0.010494230
#> gene_6211 -0.153192577 0.043691881 -0.0060494299 0.0889029246 0.045890701
#> gene_5360 -0.140786936 0.043886529 0.0490149599 -0.0446784878 -0.101817950
#> gene_6221 -0.036838380 -0.107620204 -0.1210447185 -0.0967828332 -0.034589343
#> gene_226 -0.030907753 -0.026066122 -0.1354259761 -0.1253057034 0.112995598
#> gene_2564 -0.105604456 0.071231198 0.1906314661 0.0273539183 0.053877851
#> gene_123 0.017426995 0.023282233 -0.0462883504 -0.0147625239 -0.046385349
#> gene_3603 -0.077007241 -0.187987007 0.0875111445 -0.1861801930 -0.101773344
#> gene_195 0.046249946 0.118547357 -0.1786775758 -0.0329975266 -0.178804025
#> gene_2600 0.107030536 0.053105686 -0.1285275111 0.1131140023 0.260270976
#> gene_1866 0.005948101 0.066924325 -0.1479815814 -0.2927704682 -0.127140722
#> PC26 PC27 PC28 PC29 PC30
#> value -0.0377630020 -0.0462601743 -0.0217977702 0.103630062 0.0397737975
#> gene_132 0.0423945526 -0.0599524052 0.0457419303 0.033757318 -0.0770887253
#> gene_1475 -0.0630160033 0.0381682984 -0.1391252537 0.029554916 -0.0678208864
#> gene_6915 -0.0048486087 0.0414781455 -0.0363638900 0.039459627 0.0026578021
#> gene_117 0.0180561779 -0.0863199280 -0.0079535209 -0.097976500 0.0225783504
#> gene_3068 0.0479731109 -0.1168433529 -0.0551189215 0.084396762 -0.0062815215
#> gene_2046 0.0357329257 -0.0461886113 -0.0404778477 -0.105408779 0.0949862320
#> gene_452 -0.1263691640 0.0426993909 -0.0429067881 -0.007966145 -0.0897454364
#> gene_6962 0.0169577163 -0.0395387529 0.0407970513 -0.145722283 -0.1457105612
#> gene_2773 -0.1038976311 -0.2158194518 0.2660599872 -0.073498978 -0.0261728684
#> gene_5886 0.0035070026 -0.0284593656 0.1586230716 0.147781476 -0.0113046744
#> gene_121 0.0326307427 0.0013834820 -0.0341823124 -0.166434353 -0.0490074290
#> gene_4016 0.1419936872 0.1498404363 -0.1125158130 0.038198272 -0.1598648073
#> gene_4373 0.0473838012 0.1029371702 0.0531721587 0.008453035 0.0860831227
#> gene_1194 -0.0863496204 0.0372621453 -0.1038029393 0.038861296 -0.0435564983
#> gene_1933 -0.0414913587 0.1332606994 0.0543053855 0.020411178 -0.1143422021
#> gene_4843 -0.0605107990 0.0926643416 0.1176889346 -0.117137357 -0.1258390791
#> gene_3400 0.0299661730 -0.1189258629 0.0452907709 -0.016645535 0.0082544801
#> gene_4643 0.0966948686 -0.0071369780 -0.0120147926 0.100286381 -0.0611696323
#> gene_6708 -0.0456000987 -0.0822191793 -0.0718104072 0.063053825 0.2009281855
#> gene_6086 0.0622461069 0.0843620977 -0.1149972755 -0.126934930 -0.0029757624
#> gene_6341 -0.0482326095 -0.0923548227 0.1881067639 0.007764710 -0.0429482371
#> gene_4213 -0.1259158623 0.0793166181 -0.0552422907 0.048147259 -0.0250222142
#> gene_4582 -0.1089632224 0.1658801508 0.0625763151 -0.047140764 0.1574197507
#> gene_4585 0.1331590077 0.0519692128 0.1681752792 0.043977150 -0.0410226322
#> gene_5718 0.0710047987 -0.1298642489 0.1401149398 0.054307523 -0.0746751327
#> gene_79 0.0502645248 -0.0071500959 -0.0629953382 -0.218724484 0.0712326640
#> gene_6660 -0.0472849350 0.1112862260 0.0990205144 0.020461918 -0.0839695308
#> gene_4803 -0.1227033367 0.0121390981 0.0461326889 -0.189413174 -0.0869603594
#> gene_1621 -0.0200551166 0.1358367985 -0.0349195699 -0.115678001 -0.1206483080
#> gene_2065 -0.1797720728 0.0538022599 0.0405639192 -0.076499490 -0.0165845954
#> gene_5055 -0.0653623343 0.0421182320 -0.1233270774 0.030256409 0.0801916736
#> gene_119 -0.0405068709 -0.0443169251 0.0175620959 -0.115722963 -0.1109643164
#> gene_6256 -0.0587779904 -0.0234687655 -0.0938605335 0.043356018 -0.0657411934
#> gene_1235 -0.0907789012 -0.1951612866 -0.0684188389 -0.019884389 -0.0516870343
#> gene_5764 0.2469616004 -0.0276844524 0.0273914448 0.121325608 0.1941352028
#> gene_6825 -0.1109432522 -0.2072882387 -0.1606088793 -0.002363015 -0.0735211795
#> gene_185 -0.2229230858 0.1088187416 0.0352634785 0.062664076 0.0718027677
#> gene_5691 0.0549274451 -0.1125474342 0.0536692674 -0.033168805 -0.0009770452
#> gene_2756 -0.1200055984 -0.0966461240 -0.0098556807 0.024804632 0.1321940756
#> gene_941 -0.0281641430 -0.0095875876 0.0007961752 0.098042527 0.0151576847
#> gene_3471 -0.0367634352 0.1770385329 0.0289389234 0.095339566 -0.0529181375
#> gene_2028 0.0305086592 -0.0200209013 -0.0141231698 -0.102464186 -0.1575073127
#> gene_2158 0.1807990911 -0.1618216261 0.0314575279 -0.240515919 -0.1047630304
#> gene_1384 -0.0417199997 0.0793903826 -0.0536534558 -0.122728981 0.0430118239
#> gene_3406 0.0585126126 0.0754440773 -0.0263558582 -0.077989358 -0.2060565316
#> gene_3018 -0.0099533200 0.0429995445 -0.0900599640 -0.038106426 0.0692191413
#> gene_4575 -0.0343653855 -0.0581878005 -0.1305314414 -0.247035765 -0.0887691276
#> gene_4172 -0.1028028072 0.0739699952 -0.0537890685 0.124137438 -0.0875220020
#> gene_3672 -0.0249532467 -0.0014270409 0.0411755850 0.132908610 0.0252551386
#> gene_1188 -0.0114149469 0.1223476089 0.1214623194 -0.041414714 -0.0457734824
#> gene_6557 -0.0540240172 0.0506682143 0.1277328220 0.163224979 0.0561815335
#> gene_5907 0.0042473938 -0.0803057074 -0.0323925155 -0.102568959 0.0502582012
#> gene_6651 0.0337859156 0.1097754455 -0.0301885875 -0.012305388 -0.2237779700
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#> gene_1449 0.1134984695 0.1469954882 -0.1737207545 0.120970137 -0.1840750127
#> gene_4760 -0.1008527735 -0.0454223790 0.1352342907 0.047915356 0.0198948930
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#> gene_1872 -0.1483867554 -0.0140416140 0.0536505272 -0.031557088 -0.0576017552
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#> gene_130 -0.1071451081 0.1732258489 -0.0033172793 -0.115634804 -0.0370574625
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#> gene_803 -0.0461709342 -0.1120267540 0.0330840434 0.141384836 -0.1011631664
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#> gene_1746 -0.1081708438 0.0796915107 -0.0672588683 -0.093279008 0.0454555723
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#> gene_6211 0.0043233820 -0.0848115565 -0.0548659887 0.234058533 -0.2042613044
#> gene_5360 0.0061410652 -0.0551670406 -0.1606931961 0.043217594 -0.1322997167
#> gene_6221 0.0190281636 0.0958873207 0.2181163067 -0.024089845 0.0382601745
#> gene_226 0.2042897041 0.2912882190 -0.0807014837 -0.016556734 0.1126501050
#> gene_2564 0.0311337441 -0.0564788171 -0.1836265461 0.043606901 -0.0720320763
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#> gene_3603 -0.1729419416 0.0374052631 -0.1134247521 0.078504784 0.0780592062
#> gene_195 0.0443663448 0.0011073967 -0.1097934910 -0.087309207 0.0727171232
#> gene_2600 -0.0402077831 -0.0619196082 0.0520788183 0.073164954 -0.0367469363
#> gene_1866 0.1103848371 -0.0170521456 0.0872353027 0.070045215 0.0134632456
#> PC31 PC32 PC33 PC34 PC35
#> value -0.0638477253 0.0992987252 -3.496965e-02 0.005036350 0.1672814435
#> gene_132 -0.1147364999 -0.1951203636 -1.420719e-01 -0.119202860 0.0238190085
#> gene_1475 0.1619833034 0.0557591623 3.705116e-02 0.059502137 0.0551381672
#> gene_6915 -0.0465824101 -0.0234521331 1.461541e-01 0.005902813 -0.0338625078
#> gene_117 0.0465419652 0.0308707954 -8.815563e-02 0.018017506 0.1373634883
#> gene_3068 0.1167810485 0.0240348926 -2.567324e-02 0.078702812 -0.0937462976
#> gene_2046 -0.0136293206 0.0256957361 9.112296e-02 -0.082257677 -0.0276320704
#> gene_452 0.0386045214 -0.0127306472 1.738089e-02 0.096692925 -0.0964007563
#> gene_6962 0.0357856395 0.0809030584 1.090603e-01 -0.121953812 -0.0760524910
#> gene_2773 0.0676120368 -0.0366543390 1.762768e-01 0.059455640 -0.2073560912
#> gene_5886 -0.0935373959 0.1800162515 1.010368e-01 -0.217941265 -0.0711532915
#> gene_121 0.0909782236 -0.0062217600 4.051736e-02 -0.011248198 -0.0015092203
#> gene_4016 0.0512916219 -0.1401613125 -6.633365e-02 0.113880760 0.1761831115
#> gene_4373 -0.0582188056 0.1613281463 2.139533e-01 0.022388982 0.0205671688
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#> gene_1933 0.0147715029 -0.0147231015 -4.867885e-02 0.129768644 0.2381803231
#> gene_4843 0.1064735105 0.0257251372 -5.339232e-02 0.133785168 0.0572632568
#> gene_3400 0.0329706556 -0.1007242163 -2.457645e-02 -0.017477313 0.1755066496
#> gene_4643 -0.0259729591 0.0148613436 7.772059e-02 0.074390830 -0.0734774740
#> gene_6708 0.0463294457 -0.0628817492 -1.755341e-01 -0.006165528 -0.0866576720
#> gene_6086 0.0079383944 -0.0089277819 -7.551367e-02 -0.145772209 0.1729497252
#> gene_6341 -0.0313687365 0.1217722104 -6.107700e-02 0.117066245 -0.0253376120
#> gene_4213 0.1288142074 0.0043564989 -2.556695e-02 -0.077329169 -0.1089482842
#> gene_4582 0.0652525062 -0.0411225417 -8.655537e-02 0.080637608 -0.0358647747
#> gene_4585 0.0188931632 0.0210723929 -1.597555e-01 0.101748437 0.0383496822
#> gene_5718 -0.0849279595 0.2052193369 9.134542e-02 -0.021864571 0.1638225435
#> gene_79 -0.1947647077 0.0109424983 1.604691e-01 0.059925252 -0.0285802396
#> gene_6660 -0.1209535881 0.0635297065 -4.244129e-02 -0.057710606 -0.1623839387
#> gene_4803 -0.1247439431 0.0034009883 -6.196437e-02 0.284861965 -0.1654535760
#> gene_1621 0.0349658567 0.0975789600 2.269902e-01 0.061270874 0.1370998068
#> gene_2065 -0.0911861607 -0.0969668755 1.131297e-01 -0.143527755 -0.1099356182
#> gene_5055 -0.1422020536 0.2227791012 -7.200284e-02 -0.125163182 -0.0402478614
#> gene_119 0.0987349921 -0.0127284736 3.284951e-02 0.035287049 0.0102012123
#> gene_6256 -0.0592790065 -0.2220820513 -8.735247e-02 0.130715808 -0.0480813517
#> gene_1235 0.2059961098 0.0842631716 2.473168e-02 0.049127481 -0.1266992290
#> gene_5764 -0.1601075053 -0.1625303375 3.293632e-02 0.018615817 -0.0538167189
#> gene_6825 0.0315128443 -0.0623973177 3.968861e-02 -0.100663032 -0.0202160486
#> gene_185 -0.0204112833 -0.1141753575 -3.834001e-02 -0.077436350 0.0729169425
#> gene_5691 0.0358196917 0.0075072876 -2.360740e-01 0.139595744 0.0018866227
#> gene_2756 -0.0379313384 0.0298094436 1.240832e-01 0.176617043 -0.0242130467
#> gene_941 0.0050067302 -0.2347555104 1.752857e-02 0.078856818 -0.0753090740
#> gene_3471 0.0657871640 0.1380853455 4.076525e-02 0.036649079 0.0119368721
#> gene_2028 -0.1937406253 0.1037603061 1.203954e-03 -0.022287418 -0.0402466255
#> gene_2158 -0.1221952910 -0.0577342291 -4.472976e-02 0.203588019 0.0600224466
#> gene_1384 0.0477691036 -0.0973656916 7.404392e-02 -0.057097014 0.2358375568
#> gene_3406 -0.0349906982 -0.0085546818 -7.896608e-02 0.112744561 -0.0933277019
#> gene_3018 -0.0636130617 -0.0949774941 -4.739948e-02 0.030641217 -0.0112816199
#> gene_4575 -0.0008216534 -0.0802483273 1.539738e-01 -0.047918969 -0.0234149187
#> gene_4172 0.0006680030 0.1391487674 -6.900375e-03 0.031214658 0.0829134740
#> gene_3672 -0.0283777729 -0.0240066885 3.129522e-04 0.015615004 0.1660797383
#> gene_1188 -0.0614695701 0.1785751207 8.913939e-02 0.124602549 -0.0961002283
#> gene_6557 0.1609493292 -0.1183893552 1.701535e-01 0.002827313 0.0383907538
#> gene_5907 -0.1911445980 0.1085447083 7.588257e-02 0.101601805 0.1606430369
#> gene_6651 -0.1850396701 -0.0519043978 -1.337107e-01 0.050590669 0.0646692437
#> gene_221 -0.1472519933 -0.0134454754 7.509164e-02 0.011879110 -0.0465294818
#> gene_6016 0.0233946865 -0.0142643005 -2.128974e-02 -0.126703135 0.0433769278
#> gene_1930 0.1122786027 -0.0279054452 6.550557e-02 -0.077293632 0.0075426560
#> gene_1675 0.1571592166 -0.0869467717 3.526941e-03 0.035330435 0.0929132869
#> gene_1284 -0.1677384449 0.0399158713 1.509828e-01 0.133470553 0.1245540124
#> gene_3416 0.0587751776 -0.0007768393 1.550780e-01 0.066018764 -0.0894515968
#> gene_4720 -0.1038145744 0.0426359609 -1.287026e-01 -0.059165172 0.0163010015
#> gene_1449 -0.0602988838 -0.0977998951 1.115561e-01 -0.027628632 0.0062220296
#> gene_4760 0.0104795938 -0.1070145366 5.556507e-02 -0.007362895 -0.0548274195
#> gene_6903 -0.0664144378 -0.1283220298 -2.203854e-02 -0.072479162 0.2129451806
#> gene_5141 -0.0343377656 0.0433500839 3.050864e-02 -0.270064560 -0.0926440941
#> gene_92 -0.0037850545 0.0999220387 -5.715295e-05 0.074483260 -0.0481672742
#> gene_2 0.0834106798 -0.1838277549 8.244208e-02 0.041373846 0.0767310563
#> gene_2480 0.1346345655 0.1552787508 -1.467575e-01 0.021969042 0.0604702647
#> gene_4417 0.0135504652 -0.0760198472 1.548238e-01 -0.086368931 -0.0456088326
#> gene_5327 -0.0691353542 0.0264722754 1.163207e-01 0.017875322 -0.1464664814
#> gene_3751 0.0054236022 0.0796460747 -6.304224e-03 -0.151474446 0.0006019968
#> gene_860 0.1817984421 -0.1974008295 3.455061e-02 -0.043716390 -0.0142576656
#> gene_1872 0.2071541990 0.0407674214 -6.076733e-02 0.064133032 0.1267243685
#> gene_4276 0.0200362152 0.0282747217 5.003575e-02 0.101623741 0.0981364848
#> gene_858 0.0260416744 0.1736082782 -6.373985e-02 0.127787136 0.1192949204
#> gene_1060 -0.0698144915 -0.1952352230 4.667117e-02 -0.068700363 0.0157671468
#> gene_3214 -0.0367097775 -0.1300271709 2.082536e-01 0.029884932 0.1919683048
#> gene_2378 0.0227901629 -0.0245545504 1.795634e-01 0.245776104 -0.0615044370
#> gene_3607 -0.0170150222 0.0505646711 1.157852e-02 -0.064663798 0.1547744751
#> gene_130 0.0806895448 0.1035478893 -7.894920e-02 -0.090440586 -0.1034295314
#> gene_4413 -0.1346317674 -0.0463003755 4.687479e-02 -0.008340156 0.0118651944
#> gene_803 0.0530050785 -0.1744320369 8.991160e-02 0.122714239 -0.0019758635
#> gene_4099 -0.0427115085 -0.0100939755 7.408960e-02 0.045261605 0.0169945002
#> gene_2923 -0.0582297919 0.0293998593 1.575780e-01 -0.090189527 0.0684469828
#> gene_6775 0.0406948791 0.1060233388 -1.140938e-02 -0.017712849 0.0286578210
#> gene_6040 -0.0562091033 -0.1773549255 -8.619580e-02 -0.159008550 -0.1123345555
#> gene_3191 0.0352073096 -0.0461117623 1.566772e-01 -0.073603213 0.0806016289
#> gene_1746 -0.0386947328 -0.0092547718 4.855563e-02 -0.053650559 0.1570733527
#> gene_3148 0.1635771908 0.0255713320 6.575508e-02 -0.115355639 0.0074068541
#> gene_5232 0.0524144845 0.0656967355 1.784320e-01 -0.021456327 -0.0761475776
#> gene_5696 0.0263514599 -0.0427815324 4.076078e-02 -0.138149204 -0.0465799182
#> gene_6211 0.0546063993 0.0692593088 -1.350424e-01 -0.016774190 -0.0419803024
#> gene_5360 -0.0294945481 -0.0424527680 -3.807314e-02 -0.080975074 0.0206999135
#> gene_6221 0.0256459356 -0.0550335755 -1.213823e-01 -0.053321547 -0.0053579169
#> gene_226 0.2397918286 0.0383098897 2.626533e-02 0.156143320 -0.2291883347
#> gene_2564 0.2438452511 0.1046944185 1.577393e-01 -0.013512482 0.1211364530
#> gene_123 0.1214970449 0.0042854563 -5.776203e-02 -0.014052062 -0.0491560983
#> gene_3603 -0.2669816055 0.0415330220 -3.066801e-02 0.123853314 -0.0219543945
#> gene_195 -0.0262132910 -0.0340711409 -9.045790e-02 0.001989427 -0.1202135144
#> gene_2600 0.0685313088 0.0283133046 1.825200e-02 0.116367113 0.0734996840
#> gene_1866 -0.0229279171 0.0089647841 6.093803e-02 0.100072542 0.0271663885
#> PC36 PC37 PC38 PC39 PC40
#> value -0.054617124 0.132396842 -0.139847063 -0.0082845696 0.068527050
#> gene_132 0.002481137 -0.006775995 -0.060100955 0.0167547851 -0.024993719
#> gene_1475 -0.110455800 -0.005705375 -0.217958786 -0.2782223902 0.217652723
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#> gene_117 0.027041848 -0.072842632 0.184060195 -0.0958559490 -0.126731645
#> gene_3068 -0.092523738 -0.162088766 0.065594134 -0.0192635936 -0.149505011
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#> gene_452 -0.027994652 0.072123347 -0.049222228 -0.1230706782 0.009763786
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#> gene_2773 -0.030282188 0.054182685 0.120474786 0.0094374814 0.137234698
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#> gene_6708 -0.058827635 0.026174659 0.014750518 -0.0272405282 -0.036906993
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#> gene_4213 0.082868564 -0.119982048 -0.102906843 0.1128684940 -0.103969149
#> gene_4582 0.045895654 0.040881939 0.064138209 -0.0115286573 0.062285465
#> gene_4585 -0.016165592 -0.142439109 -0.032894891 -0.0893851392 0.077320921
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#> gene_79 -0.012151998 0.060239131 -0.023576170 -0.0778784817 -0.100490537
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#> gene_5055 -0.086865015 0.023998202 -0.031828959 0.1426069936 0.055096733
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#> gene_5764 0.191874576 0.064019469 -0.074934411 0.1445757094 0.039585457
#> gene_6825 0.059799654 -0.130674863 -0.065782097 -0.0904132080 -0.004092032
#> gene_185 -0.051272585 0.037069429 -0.040285937 0.0164689280 -0.103652864
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#> gene_2756 -0.092331506 -0.039143271 -0.177548003 0.0826770333 -0.059217775
#> gene_941 -0.170802339 0.013223344 0.034224689 0.0301016187 0.169319490
#> gene_3471 0.042556108 0.002664138 0.006406248 0.0806665004 0.054079127
#> gene_2028 -0.035335513 0.164101966 -0.082436991 0.0364983446 0.004917344
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#> gene_1384 -0.003128008 -0.069259352 -0.020462507 -0.0677905505 0.176023383
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#> gene_4575 -0.005030768 0.015995868 0.113000820 0.0649479769 -0.004605156
#> gene_4172 0.078068551 0.016591065 -0.200575610 -0.0678132130 0.043988342
#> gene_3672 -0.072765609 -0.010098829 0.203994113 -0.0541969076 0.078044254
#> gene_1188 -0.126823325 0.067423749 0.021436431 -0.1317327156 0.083435695
#> gene_6557 -0.053564808 0.068736800 -0.075004190 -0.1401107502 -0.017711944
#> gene_5907 0.197931245 -0.067356343 0.213375318 0.2616113450 0.024871708
#> gene_6651 -0.041868208 -0.042857938 0.055226866 -0.0326432751 0.007183706
#> gene_221 -0.094920946 0.086571546 -0.006224010 -0.1816060256 -0.006287486
#> gene_6016 0.072362929 0.114935738 -0.171483506 -0.1134404323 0.097187335
#> gene_1930 -0.027935759 0.088735446 -0.032552843 -0.0995264845 -0.113636329
#> gene_1675 0.100934921 0.220545972 -0.165099058 -0.0644035830 0.094299866
#> gene_1284 0.059214710 -0.219792518 -0.027508474 -0.0973229492 0.009693483
#> gene_3416 -0.143337320 0.016957921 0.179949493 0.0404350682 0.132395999
#> gene_4720 -0.049700513 0.142402910 -0.029932360 -0.1323462371 -0.081991186
#> gene_1449 0.047932710 0.041471202 0.004468906 0.0397313378 -0.131040910
#> gene_4760 0.038468084 0.075853309 0.049313529 0.0223531427 -0.114978673
#> gene_6903 -0.079055423 -0.044040984 0.098085865 -0.1293241284 -0.273623844
#> gene_5141 -0.266832289 -0.095573306 0.077332202 0.0553392922 0.136609381
#> gene_92 -0.076947321 -0.121096788 -0.048154849 0.0065254957 0.122809966
#> gene_2 -0.076103377 -0.032909753 0.020447486 0.1510809003 0.185455309
#> gene_2480 -0.073336572 0.183243105 0.144203284 -0.0542202217 0.082584806
#> gene_4417 0.011710519 0.016798414 -0.036281101 0.0209388262 -0.180383666
#> gene_5327 0.116724731 0.224860169 -0.293932817 0.1319359118 -0.088392612
#> gene_3751 0.178050342 -0.045220972 -0.056998137 -0.0463910686 0.077535460
#> gene_860 -0.098077088 0.223493990 0.031755286 0.2063503034 0.166101010
#> gene_1872 -0.031082646 0.095683189 0.022474117 -0.0202379098 -0.203060316
#> gene_4276 0.050934257 -0.142296169 0.009362321 -0.0610026562 0.163519630
#> gene_858 -0.011108916 0.089164926 0.013698235 -0.0243267221 0.060449483
#> gene_1060 -0.148373390 0.194223727 0.064589120 -0.1322299477 0.024848904
#> gene_3214 -0.244017784 -0.004585052 -0.100794920 0.0411302360 -0.017284079
#> gene_2378 0.003174045 0.027105349 -0.042395814 0.0614342393 -0.005886550
#> gene_3607 -0.044039526 0.015246422 -0.071006250 0.1944516068 0.028730792
#> gene_130 0.015377906 0.063764168 -0.190118155 0.1461629331 0.028650116
#> gene_4413 -0.206717248 0.048877136 -0.125133224 -0.0456355371 -0.154023212
#> gene_803 0.038792945 -0.116111699 -0.080259277 0.1098603676 -0.051744981
#> gene_4099 -0.021691855 -0.031469762 0.061007247 -0.1196706842 -0.071153498
#> gene_2923 -0.098798411 0.031933883 0.037289229 0.2184754821 -0.037917945
#> gene_6775 -0.071890793 -0.008561168 0.104010623 0.0703331331 -0.014528891
#> gene_6040 -0.161703522 -0.096373768 -0.017902081 0.1244728451 0.079632067
#> gene_3191 0.041046353 0.179288827 0.022033694 -0.0579137837 0.015070127
#> gene_1746 0.095321223 -0.053280714 0.088262726 0.0599847645 0.057270226
#> gene_3148 0.203002865 -0.006689919 0.065521967 -0.0293841474 -0.229297890
#> gene_5232 0.054558700 0.047970484 -0.150518106 -0.0091754015 -0.055963878
#> gene_5696 0.063060721 -0.110504357 0.089661043 -0.0567276189 0.009440334
#> gene_6211 0.020995907 0.216752479 0.181712373 0.0925165019 -0.063847476
#> gene_5360 -0.142039290 0.076267440 -0.017353336 -0.1261336672 0.039194704
#> gene_6221 0.020472148 -0.080453154 0.067665924 -0.0324567618 -0.072618642
#> gene_226 0.018387056 -0.091693781 0.148085703 0.0683803397 -0.021476388
#> gene_2564 -0.126066386 0.031038142 0.009440335 0.0503744736 -0.117686436
#> gene_123 -0.004956830 -0.079344433 0.015565295 0.1515556959 0.013257845
#> gene_3603 0.075050683 0.126505348 0.092373526 -0.0132993558 -0.052750818
#> gene_195 0.152823073 0.017349194 0.042102500 -0.1051477793 0.004173899
#> gene_2600 0.043355284 0.057249367 0.001464516 -0.0012432809 0.005468721
#> gene_1866 -0.165739738 -0.035377830 0.008836661 0.1236990196 -0.085969775
#> PC41 PC42 PC43 PC44 PC45
#> value -0.016954479 -0.1428369329 0.0660190870 0.0552705148 -0.1089502297
#> gene_132 0.114203604 0.1187330258 0.0820476223 -0.0695397656 0.0610265932
#> gene_1475 0.073026759 0.0498700927 0.0474989675 0.0655602816 -0.0371752961
#> gene_6915 -0.034153821 0.0340400767 0.1248494367 -0.1359287448 -0.0629492035
#> gene_117 0.014430702 -0.0865350123 0.0055762616 -0.0040779075 -0.1215943135
#> gene_3068 -0.146267444 -0.0903978901 -0.1029867968 -0.1159927138 -0.0451171474
#> gene_2046 -0.047702518 0.0202521705 0.0552120426 -0.1192127141 -0.0566755555
#> gene_452 -0.042415520 -0.0864560996 -0.1126415416 -0.0373760838 -0.1057973810
#> gene_6962 -0.075213365 0.1629438682 0.0032660970 0.0808885931 0.2155355807
#> gene_2773 0.075534866 -0.2940861346 0.1050850793 0.0895084929 0.1005843817
#> gene_5886 0.034880981 -0.0067728912 -0.0543115022 -0.1632240633 0.1166575275
#> gene_121 0.061226562 -0.0081330273 -0.0123118749 0.0300306867 -0.0866822029
#> gene_4016 0.011542127 0.0373607228 -0.0536485041 0.0205680041 0.0181537719
#> gene_4373 0.127720664 -0.0846336714 0.0520300922 -0.0083691181 0.0913065802
#> gene_1194 0.096798731 0.0278326539 -0.0657202568 -0.0944846600 -0.0262912847
#> gene_1933 -0.035755199 -0.1370978335 0.0264654676 -0.0169628335 0.0145837318
#> gene_4843 0.166609964 -0.0058345833 -0.0927805423 -0.1599636919 -0.0531474233
#> gene_3400 0.171301548 -0.0638826353 -0.0967591669 -0.0716368293 0.1106137269
#> gene_4643 0.009381699 0.1819348147 -0.0476759412 0.0935554995 0.0937975330
#> gene_6708 0.063778756 0.0842602714 0.0189933907 0.2078770792 0.0163713878
#> gene_6086 0.056971164 -0.0203614882 0.1245818363 0.0421966106 -0.2090159336
#> gene_6341 -0.012575597 0.1055649817 -0.2034226014 -0.0699105926 -0.1285195763
#> gene_4213 -0.112277703 0.1158968215 0.0227309558 0.0346032193 0.0692245603
#> gene_4582 0.022847181 0.0175039556 0.0190958614 -0.0574057073 -0.0084177381
#> gene_4585 -0.024462802 -0.0639239215 -0.1081981789 0.0714850489 -0.1308717064
#> gene_5718 0.112465174 0.3136766903 0.1045954625 0.0020336908 -0.1559227604
#> gene_79 -0.019282049 0.0519445425 -0.0883279573 0.3541589558 0.0079787496
#> gene_6660 -0.142614760 -0.0137315780 0.2110930361 -0.0227682939 -0.0033182259
#> gene_4803 0.103513581 -0.0050512553 -0.0002851148 -0.0758867667 0.0940713033
#> gene_1621 0.091953729 -0.1220057647 -0.0407904538 0.2208866022 -0.1120907987
#> gene_2065 0.069167873 -0.0118101010 -0.0803511881 0.0032489138 -0.0806665099
#> gene_5055 -0.111968222 -0.1550857965 -0.0088532813 -0.0144020455 0.0536613946
#> gene_119 -0.127006403 0.0956126360 0.0287108904 -0.0130352630 -0.0565370905
#> gene_6256 0.090187976 -0.0178835756 0.1441346344 0.1702429246 -0.0054675687
#> gene_1235 0.114297217 0.1171854012 -0.0396455148 0.0664911984 0.1915141547
#> gene_5764 -0.095188329 0.0671560644 -0.2390467048 0.0806938543 -0.0522825243
#> gene_6825 0.025419077 -0.0041483446 0.0892444720 0.0541123540 -0.0246138123
#> gene_185 0.099605572 -0.1495851535 -0.0141792072 -0.0928521492 0.1281611459
#> gene_5691 -0.168920438 -0.1981002729 -0.0567555992 -0.1172551739 0.2141187222
#> gene_2756 -0.013516054 0.2640706517 -0.0235907923 -0.0088938564 0.0400252719
#> gene_941 -0.014958016 0.0125456710 0.0812168121 0.0288832819 -0.0644083064
#> gene_3471 -0.040787390 0.0162997868 -0.0967004437 -0.0159729649 0.1293149018
#> gene_2028 -0.068777236 -0.0266837748 -0.1844067067 -0.0007092214 0.0491688856
#> gene_2158 0.157340175 0.0422937840 0.1550120312 -0.1600544380 0.1461668992
#> gene_1384 -0.152172989 0.0119343356 0.0406154713 -0.0180723114 0.2630737282
#> gene_3406 -0.209985244 -0.0029357521 -0.0332658194 -0.1880219255 -0.1584094730
#> gene_3018 0.023250206 -0.1434034068 -0.0916227601 -0.1320138242 0.0756941999
#> gene_4575 -0.044280977 0.1037210434 0.0072654629 -0.1227469369 -0.1495616756
#> gene_4172 -0.014501012 0.1358050297 0.0979068316 -0.1388200694 0.0164530885
#> gene_3672 -0.231362438 0.0548029223 -0.0127868225 -0.0077620657 0.0415352793
#> gene_1188 -0.111926805 -0.0904740239 -0.0669937031 0.0421916360 -0.0412945072
#> gene_6557 0.078712458 0.0694570322 0.0091746799 -0.2744740371 -0.2510565613
#> gene_5907 0.017620041 -0.0397335106 0.0565518070 -0.0768267649 -0.1279955730
#> gene_6651 -0.208472243 0.2008355467 -0.0582679254 0.0346607118 -0.0301931114
#> gene_221 0.036637416 -0.0487634706 -0.0294183519 -0.0502456343 0.0792314233
#> gene_6016 -0.081835994 0.0816234831 -0.0872672101 0.1293664966 -0.0334059601
#> gene_1930 -0.059346056 0.1638619992 -0.0109081070 -0.1442197461 0.0976197482
#> gene_1675 -0.006079212 0.0859868031 -0.0724832835 0.1466390820 -0.0399510293
#> gene_1284 0.089537304 -0.0649446314 -0.0375917552 -0.0006542967 0.0347616756
#> gene_3416 -0.053072087 0.0803577568 -0.0111937739 -0.1257633904 0.0752153989
#> gene_4720 0.212970307 -0.1047994763 0.0064529517 0.1221218062 -0.0891102425
#> gene_1449 0.041132987 -0.0958498802 0.0837435776 0.0233748840 0.0589656716
#> gene_4760 0.070773814 -0.0655574727 0.0231506701 0.0318094424 0.0562228529
#> gene_6903 0.005625680 0.0646397988 0.0360225232 -0.1478136645 0.0927303795
#> gene_5141 0.205868328 -0.0587608379 -0.1469679666 0.0112269753 -0.0821753155
#> gene_92 0.119329486 0.1070557027 -0.1493134585 0.0746361945 0.0081291357
#> gene_2 -0.009695862 -0.0488754962 -0.1069612696 -0.0924192196 -0.0046361872
#> gene_2480 0.017058595 -0.0226100770 -0.1294770258 -0.1067877970 -0.0698581122
#> gene_4417 -0.011640763 -0.1828008229 0.0385184199 -0.1063230511 -0.1672985213
#> gene_5327 -0.148391960 0.0709279200 0.1578188655 -0.0351399051 -0.1144403339
#> gene_3751 -0.141214326 -0.0923845474 0.0639755351 0.0516237034 -0.0179935554
#> gene_860 -0.100986819 0.0250328346 0.1403075807 0.0636821891 -0.0372259734
#> gene_1872 -0.026232760 0.0430744393 -0.2312831094 0.0785717486 0.0398817874
#> gene_4276 0.062046301 0.1138502868 -0.0860688174 -0.0928409569 -0.0003529771
#> gene_858 0.010656540 -0.1149330467 0.0696249861 0.1570802811 -0.0724175683
#> gene_1060 0.103501394 0.0273201437 -0.0997467388 0.1026949502 0.0181605657
#> gene_3214 -0.137790609 0.0008905326 0.0421264525 0.0740975316 0.1383434285
#> gene_2378 -0.010908958 0.0277423808 0.0394414413 0.1277747643 -0.0573094425
#> gene_3607 0.076263609 -0.0246084627 -0.0352582720 0.0290678882 -0.0974583113
#> gene_130 0.142606417 -0.0520507761 0.1008908595 -0.0056565474 -0.0443120327
#> gene_4413 -0.069741914 0.1016716639 0.0289981587 0.0409894109 -0.0799441830
#> gene_803 -0.155594908 -0.1881451188 -0.1078543865 0.0884626112 -0.1660625617
#> gene_4099 -0.176098708 -0.1475591659 0.0405756157 -0.0261951863 -0.0549815072
#> gene_2923 0.115054340 -0.0064404508 -0.3107054148 0.0043080219 0.0170942461
#> gene_6775 -0.090950674 0.0187476469 0.0250495924 -0.0161464347 -0.2199184523
#> gene_6040 -0.012755642 0.0934780725 -0.2185601796 0.0107065572 -0.2320255260
#> gene_3191 0.149162442 -0.0846303483 -0.0288028164 -0.0370931403 0.0107507107
#> gene_1746 -0.095221836 0.0064714126 -0.0529433653 0.1354016402 0.1116447750
#> gene_3148 -0.161626369 -0.0428555576 -0.0178820964 0.0488181371 -0.0601417872
#> gene_5232 -0.146431467 -0.1127039903 -0.0740355905 -0.1025612899 0.0997580225
#> gene_5696 -0.029145531 -0.0152344418 -0.0722303232 -0.0054499533 -0.0071333834
#> gene_6211 0.019914312 0.0480180751 0.1271107925 0.0576840833 0.0501599182
#> gene_5360 -0.087500912 -0.0238095247 -0.0589747490 -0.0391364031 -0.0555536425
#> gene_6221 0.016987648 0.0661479462 0.2078995790 0.0734542221 -0.0413368601
#> gene_226 0.122535579 0.0119119925 0.0106248937 0.0772194127 -0.0424605061
#> gene_2564 0.071762007 0.0963982487 0.0941979248 -0.0640881504 -0.0302782249
#> gene_123 -0.038654081 0.0357377675 -0.1167128177 0.0965325225 0.0348279559
#> gene_3603 0.040779910 0.1050003517 0.0016721210 -0.0318938939 -0.0976421773
#> gene_195 0.145556866 0.0216246548 -0.0128875496 -0.1667450654 -0.0192602578
#> gene_2600 -0.023206060 -0.0520353649 -0.0547768734 -0.0713726223 -0.0570768164
#> gene_1866 -0.021860466 -0.0380336672 0.2462563395 0.0691649961 -0.0815406486
#> PC46 PC47 PC48 PC49
#> value 0.0762720221 0.053699050 -0.010477221 0.088586948
#> gene_132 -0.0848940568 0.193952194 -0.195198903 -0.003973558
#> gene_1475 -0.1340395175 -0.064075782 -0.132991369 0.048534757
#> gene_6915 0.0881171833 0.008752858 0.012435915 -0.017086052
#> gene_117 -0.0097230473 -0.087597481 -0.105270722 0.131286360
#> gene_3068 0.0848370132 -0.080451221 0.045495916 -0.022157449
#> gene_2046 -0.1419963007 -0.184321007 0.346797292 -0.109010133
#> gene_452 0.1442854111 0.173268156 -0.016514194 -0.072794801
#> gene_6962 0.1351259766 0.148586657 0.066317599 0.001384077
#> gene_2773 -0.0267214108 -0.008637948 -0.042391658 -0.184232716
#> gene_5886 -0.0640389344 0.117103233 0.030962042 0.089932496
#> gene_121 -0.0327679708 -0.063617870 -0.038981394 0.109376500
#> gene_4016 -0.1191203761 0.063805789 0.164004670 -0.218631436
#> gene_4373 0.0023898732 0.142221729 -0.027241672 0.077736620
#> gene_1194 0.0214686095 -0.055561925 0.063021765 0.191255046
#> gene_1933 -0.1417925763 -0.020288724 0.119564765 -0.143754947
#> gene_4843 0.1556663256 0.122341849 0.058785368 -0.051293236
#> gene_3400 -0.0473167770 -0.002786652 -0.039986277 0.045845608
#> gene_4643 0.0456665156 -0.120410398 -0.055185367 0.155886199
#> gene_6708 0.1814721436 0.151752121 0.050464406 0.080747767
#> gene_6086 0.1192794833 0.048083620 -0.186847667 0.198802625
#> gene_6341 0.1182212571 -0.048344418 0.056613330 -0.021049257
#> gene_4213 0.0730370207 0.034423460 0.079605105 -0.139552250
#> gene_4582 -0.0469837719 0.141842518 -0.139997718 -0.076003712
#> gene_4585 -0.1745034694 -0.058268337 0.073690589 0.044389259
#> gene_5718 -0.0217303954 -0.095097891 0.005298626 -0.004962782
#> gene_79 0.0997695574 0.009604056 0.029716182 0.056558710
#> gene_6660 -0.1515585287 -0.043486541 0.099943456 0.045999461
#> gene_4803 -0.0178079380 -0.198058074 -0.060347410 0.058252908
#> gene_1621 -0.0728132809 -0.182976489 0.114063075 0.004261276
#> gene_2065 0.0099735299 -0.133166358 0.057483973 -0.034557435
#> gene_5055 0.1611273426 -0.162191501 -0.222436171 -0.030595254
#> gene_119 -0.1196525399 0.103914350 -0.126346540 -0.036412626
#> gene_6256 0.0339826302 -0.060392405 -0.140973018 -0.143844245
#> gene_1235 -0.1021183802 -0.019498047 0.029707011 0.160357015
#> gene_5764 0.0277700979 -0.074752075 -0.017723969 -0.148746417
#> gene_6825 0.0807942862 0.026902768 0.200929093 -0.010624447
#> gene_185 0.1230766826 -0.068202236 -0.026305687 0.207393768
#> gene_5691 0.0485395909 -0.173810186 0.018038053 0.174711090
#> gene_2756 -0.1652834661 -0.049188815 -0.231708239 -0.153714696
#> gene_941 0.0381225555 -0.063977550 -0.012677162 0.106561241
#> gene_3471 -0.0037482913 0.030461134 0.044164767 0.171118361
#> gene_2028 -0.1440886873 0.178464726 0.021736418 -0.080706157
#> gene_2158 0.0414502135 0.005609844 -0.022691343 0.129083433
#> gene_1384 -0.0719084167 0.050601840 0.021088876 0.069065049
#> gene_3406 0.0472347677 -0.004253060 -0.048383421 0.048400596
#> gene_3018 -0.2606968796 -0.002915559 0.051147348 0.040905992
#> gene_4575 -0.0120369619 0.187096882 0.140791003 0.066629838
#> gene_4172 0.1019123815 -0.214372649 -0.005963213 0.070906670
#> gene_3672 0.1396543365 0.030678804 0.090284097 0.189114958
#> gene_1188 0.0380535651 0.257575354 -0.138373021 0.001651873
#> gene_6557 0.1197693289 -0.028723599 -0.131894159 0.024328106
#> gene_5907 0.0065399036 -0.017379198 -0.058099423 0.085413368
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